Cheap flights from Detroit to San Francisco from C$ 268

The cheapest month to fly to San Francisco from Detroit is in January. Flight prices, which tend to average around C$ 567, are often lower during this time because this is during the off-season. The month of February is another great option to travel to San Francisco, with average flight prices from Detroit averaging around C$ 580.

The cheapest day to depart from Detroit to San Francisco is on a Wednesday. Travellers who choose to depart for San Francisco on a Wednesday will often find tickets for as low as C$ 549. On the other hand, Sunday is the most expensive day to depart from Detroit because it is more convenient for both business and leisure travellers. As a result, prices tend to be around C$ 1,436.

Flying to San Francisco from Detroit in the evening is the least expensive time of day to depart. momondo users have found prices as low as C$ 709 when looking at flights departing in the evening. In contrast, the most expensive time of day to depart to San Francisco is in the afternoon when prices are around C$ 908.

Fly from Detroit Metropolitan Wayne County to San Francisco for the best Detroit - San Francisco flight prices

You are more likely to see cheaper flights to San Francisco from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around C$ 639 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Detroit for as low as C$ 433 on momondo.

There are 3 cabin classes available to choose from on Detroit to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 48% on your flight if you consider stops on a Detroit to San Francisco flight.

As of July 2026, prices for Detroit to San Francisco flights are approximately 24% cheaper when compared to flights at the same time last year.

Southwest is the most popular carrier operating from Detroit to San Francisco

United Airlines, Delta and Frontier are the top three most popular airlines that fly to San Francisco from Detroit according to our data. United Airlines is the first choice among our users, with 32% of people opting to fly with this airline when travelling to San Francisco. Keep in mind that there are 5 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

The number of flights available between Detroit and San Francisco is 17 per day as of July 2026. The most frequent departure time is 4:00p.m., with 48% of daily flights leaving in the afternoon.

125 flights are operational weekly from Detroit to San Francisco as of July 2026. The most popular departure day for this route is Mon, with 18% of flights per week taking off on this day.